{"id":38136,"date":"2019-06-24T12:00:11","date_gmt":"2019-06-24T10:00:11","guid":{"rendered":"https:\/\/aktuelles.uni-frankfurt.de\/?p=38136"},"modified":"2023-02-22T17:37:36","modified_gmt":"2023-02-22T16:37:36","slug":"study-shows-mri-on-par-with-cardiac-catheterization","status":"publish","type":"post","link":"https:\/\/aktuelles.uni-frankfurt.de\/en\/english\/study-shows-mri-on-par-with-cardiac-catheterization\/","title":{"rendered":"Study shows: MRI on par with cardiac catheterization"},"content":{"rendered":"<div class=\"wp-block-image\"><figure class=\"alignleft is-resized\"><img decoding=\"async\" src=\"https:\/\/aktuelles.uni-frankfurt.de\/wp-content\/uploads\/2019\/06\/beitrag_mrt-herzkatheter.jpg\" alt=\"\" class=\"wp-image-38132\" height=\"485\" srcset=\"https:\/\/aktuelles.uni-frankfurt.de\/wp-content\/uploads\/2019\/06\/beitrag_mrt-herzkatheter.jpg 283w, https:\/\/aktuelles.uni-frankfurt.de\/wp-content\/uploads\/2019\/06\/beitrag_mrt-herzkatheter-200x300.jpg 200w\" sizes=\"(max-width: 283px) 100vw, 283px\" \/><figcaption> Above: Measuring blood flow in the myocardium with magnet resonance imaging (top). The dark area in the myocardium (arrows) shows a pronounced reduction of blood flow. The cardiac catheterization of the same patient (bottom) shows a clear constriction of the artery.  Credit: Eike Nagel, Goethe University<\/figcaption><\/figure><\/div>\n\n\n\n<p>The non-invasive measurement of blood flow\nto the heart using magnetic resonance imaging (MRI) is on par with cardiac\ncatheterization. This was the result of an international study published in the\ncurrent issue of the New England Journal of Medicine and headed by researchers\nfrom Goethe University.<\/p>\n\n\n\n<p>For patients with chest pain and presumably\nstable coronary heart disease (CHD), therapy depends primarily on how constricted\nthe arteries that support the heart are (coronary arteries). This is often determined\nusing an invasive procedure called cardiac catheterization. If necessary, the\npressure in the coronary arteries is also measured. The combination of these\nmethods is the currently the recognized standard for making therapy decisions. Cardiovascular\nmagnetic resonance imaging (MRI) is an alternative for directly measuring the\nblood flow in the myocardium. <\/p>\n\n\n\n<p>In contrast to cardiac catheterization, MRI\nis non-invasive, works without ionising radiation, can be done in 40 minutes\nand delivers direct measurements of the blood flow to the heart. The team\nheaded by Professor Eike Nagel, Director of the Institute for Experimental and\nTranslational Cardio Vascular Imaging at Goethe University was able to\ndemonstrate that MRI measurements are as safe to guide decision-making as the\ncurrently used invasive procedure. Within the international MR-INFORM study,\nthey examined 918 patients with an indication for cardiac catheterization to\nsee if decision-making by an MRI scan led to the same results as the current\ninvasive method.<\/p>\n\n\n\n<p>Patients were randomly assigned to two\ngroups. One group received the standard diagnostic investigation with cardiac\ncatheterization and pressure measurement of the coronary arteries. The other\nhad the 40 minute MRI scan of the heart to decide whether to send the patient\non for invasive angiography.<\/p>\n\n\n\n<p>In each study arm, constricted coronary\nvessels were dilated when indicated by the examination. In the following year,\nthe physicians documented how many patients died, suffered a heart attack or\nrequired a repeated vascular dilation. In addition, they recorded whether the\nheart symptoms continued.<\/p>\n\n\n\n<p>The result: in the group of patients examined\nby MRI, less than half required a diagnostic cardiac catheterization and fewer\npatients received a vascular dilation (36% vs 45 %). This means that with a\nfast and non-invasive MRI examination as the first test, both diagnostic and\ntherapeutic cardiac catheterizations can be reduced. Importantly, the two\ngroups did not differ in terms of continuing symptoms, the development of new\nsymptoms, complications, or deaths.<\/p>\n\n\n\n<p>\u201cThis means that patients with stable\nchest pains who previously would have received cardiac catheterization can\nalternatively be examined with MRI,\u201d concludes Professor Eike Nagel. \u201cThe\nresults for the patients are just as good, but an examination by MRI has many\nadvantages: the procedure takes about 40 minutes, patients merely receive a\nsmall cannula in their arm and are not subject to radiation.\u201d The physician\nhopes that the less invasive method will now be used as a method of first\nchoice, reducing the need for cardiac catheterizations.<\/p>\n\n\n\n<p>In contrast to Great Britain, where an MRI\nscan of the heart is paid for by the National Health Service (NHS), reimbursement\nis often difficult in Germany and usually has to be negotiated individually. In\nthis regard, Nagel also hopes that the study will contribute to the acceptance\nof the non-invasive procedure and improve its availability.<\/p>\n\n\n\n<p>Financial support was provided primarily by\nthe British National Institute of Health Research (NIHR) via the Biomedical\nResearch Centre (BRC) at Guy\u2019s &amp; St. Thomas\u2019 Hospital, the German Centre\nfor Cardiovascular Research (DZHK) and the company Bayer AG Deutschland.<\/p>\n\n\n\n<p>Caption: Measuring blood flow in the\nmyocardium with magnet resonance imaging (top). The dark area in the myocardium\n(arrows) shows a pronounced reduction of blood flow. The cardiac\ncatheterization of the same patient (bottom) shows a clear constriction of the\nartery. <\/p>\n\n\n\n<p class=\"has-background has-very-light-gray-background-color\"><strong>Publikation: <\/strong>Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease  Eike Nagel, et al.<br><br>N Engl J Med 2019;380:2418-28.  <br>DOI: 10.1056\/NEJMoa1716734 <\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>The non-invasive measurement of blood flow to the heart using magnetic resonance imaging (MRI) is on par with cardiac catheterization. This was the result of an international study published in [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":38131,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":"","_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"footnotes":""},"categories":[126,254],"tags":[247],"post_folder":[],"class_list":["post-38136","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-english","category-research","tag-medicine"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Study shows: MRI on par with cardiac catheterization | Aktuelles aus der Goethe-Universit\u00e4t Frankfurt<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/aktuelles.uni-frankfurt.de\/en\/english\/study-shows-mri-on-par-with-cardiac-catheterization\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study shows: MRI on par with cardiac catheterization | Aktuelles aus der Goethe-Universit\u00e4t Frankfurt\" \/>\n<meta property=\"og:description\" content=\"The non-invasive measurement of blood flow to the heart using magnetic resonance imaging (MRI) is on par with cardiac catheterization. This was the result of an international study published in [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aktuelles.uni-frankfurt.de\/en\/english\/study-shows-mri-on-par-with-cardiac-catheterization\/\" \/>\n<meta property=\"og:site_name\" content=\"Aktuelles aus der Goethe-Universit\u00e4t Frankfurt\" \/>\n<meta property=\"article:published_time\" content=\"2019-06-24T10:00:11+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-02-22T16:37:36+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/aktuelles.uni-frankfurt.de\/wp-content\/uploads\/2019\/06\/beitragsbild_mrt-herzkatheter.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"650\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"-\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"-\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/\"},\"author\":{\"name\":\"-\",\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/#\\\/schema\\\/person\\\/8e55ea338fb65d1ce87a91565d1f1739\"},\"headline\":\"Study shows: MRI on par with cardiac catheterization\",\"datePublished\":\"2019-06-24T10:00:11+00:00\",\"dateModified\":\"2023-02-22T16:37:36+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/\"},\"wordCount\":685,\"publisher\":{\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/beitragsbild_mrt-herzkatheter.jpg\",\"keywords\":[\"Medicine\"],\"articleSection\":[\"English\",\"Research\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/\",\"url\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/\",\"name\":\"Study shows: MRI on par with cardiac catheterization | Aktuelles aus der Goethe-Universit\u00e4t Frankfurt\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/beitragsbild_mrt-herzkatheter.jpg\",\"datePublished\":\"2019-06-24T10:00:11+00:00\",\"dateModified\":\"2023-02-22T16:37:36+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/english\\\/study-shows-mri-on-par-with-cardiac-catheterization\\\/#primaryimage\",\"url\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/beitragsbild_mrt-herzkatheter.jpg\",\"contentUrl\":\"https:\\\/\\\/aktuelles.uni-frankfurt.de\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/beitragsbild_mrt-herzkatheter.jpg\",\"width\":650,\"height\":450,\"caption\":\"Oben: Durchblutungsmessung des Herzmuskels mit Magnetresonanztomographie. Der dunkle Bereich im Herzmuskel (Pfeile) zeigt eine ausgepr\u00e4gte Durchblutungsst\u00f6rung an. Unten: Herzkatheteruntersuchung des gleichen Patienten. Eine Arterie zeigt eine deutliche Engstelle. Diese kann aufgedehnt und mit einer Gef\u00e4\u00dfst\u00fctze (Stent) versorgt werden. 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