{"id":84586,"date":"2025-06-27T08:59:02","date_gmt":"2025-06-27T06:59:02","guid":{"rendered":"https:\/\/aktuelles.uni-frankfurt.de\/?p=84586"},"modified":"2025-06-27T08:59:31","modified_gmt":"2025-06-27T06:59:31","slug":"rna-researchers-from-frankfurt-and-grenoble-receive-franco-german-science-award","status":"publish","type":"post","link":"https:\/\/aktuelles.uni-frankfurt.de\/en\/english\/rna-researchers-from-frankfurt-and-grenoble-receive-franco-german-science-award\/","title":{"rendered":"RNA Researchers from Frankfurt and Grenoble Receive Franco-German Science Award"},"content":{"rendered":"<p><strong>RNA researchers Prof. Stefanie Kaiser from Goethe University Frankfurt and Dr. Eva Kowalinski from EMBL in Grenoble, France, have been awarded the Franco-German science prize \u201cPrix Forcheurs Jean-Marie Lehn\u201d. The award, first presented in 2017 by the Franco-German University (FGU) and the French Embassy in Germany, comes with a total prize money of \u20ac20,000. This year\u2019s award recognizes the two scientists\u2019 joint research project focused on identifying new cancer therapeutics by modifying RNA structures.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"650\" height=\"450\" src=\"https:\/\/aktuelles.uni-frankfurt.de\/wp-content\/uploads\/2025\/06\/beitragsbild_2025_0624_Prix-Forcheurs_KaiserKowalinski-01.jpg\" alt=\"\" class=\"wp-image-84585\" srcset=\"https:\/\/aktuelles.uni-frankfurt.de\/wp-content\/uploads\/2025\/06\/beitragsbild_2025_0624_Prix-Forcheurs_KaiserKowalinski-01.jpg 650w, https:\/\/aktuelles.uni-frankfurt.de\/wp-content\/uploads\/2025\/06\/beitragsbild_2025_0624_Prix-Forcheurs_KaiserKowalinski-01-300x208.jpg 300w, https:\/\/aktuelles.uni-frankfurt.de\/wp-content\/uploads\/2025\/06\/beitragsbild_2025_0624_Prix-Forcheurs_KaiserKowalinski-01-500x346.jpg 500w, https:\/\/aktuelles.uni-frankfurt.de\/wp-content\/uploads\/2025\/06\/beitragsbild_2025_0624_Prix-Forcheurs_KaiserKowalinski-01-18x12.jpg 18w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/><figcaption class=\"wp-element-caption\">The two awardees: Dr. Eva Kowalinski, EMBL Grenoble (holding a model of a tRNA molecule), and Prof. Dr. Stefanie Kaiser, Goethe University Frankfurt. Photo: French Embassy in Germany<\/figcaption><\/figure>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The \u201cPrix Forcheurs Jean-Marie Lehn\u201d was presented on June 24, 2025, at the auditorium of the French Embassy. It honors the collaborative work of a research duo from Germany and France working in the fields of chemistry, biochemistry, pharmacy, and medicine. Sanofi Germany and BASF France contributed the prize money, awarding \u20ac10,000 to each laureate.<\/p>\n\n\n\n<p>As part of the project titled \u201cFighting cancer by targeting the epitranscriptome,\u201d Stefanie Kaiser and Eva Kowalinski are researching how the modification of tRNA may enable more effective treatment of liver and breast cancer. tRNA molecules are essential carriers that ensure the correct translation of genetic information \u2013 encoded on mRNA \u2013 into proteins, the building blocks of our cells. Chemical modifications to tRNAs are highly diverse; they are critical for maintaining the molecules\u2019 structural integrity and ensuring accurate and efficient decoding of genetic information. Errors in these modifications can lead to numerous diseases. The labs of Kowalinski and Kaiser are collaborating to decode the function of a specific group of enzymes that catalyze these tRNA modifications. Their goal is to understand how these enzymes work as well as how they recognize and distinguish between different tRNAs. The research teams will also develop small molecules designed to specifically target these enzymes, aiming to explore their therapeutic potential.<\/p>\n\n\n\n<p>Awardee Dr. Eva Kowalinski stated: \u201cI know I speak for both of us when I say that receiving the \u2018Prix Forcheurs Jean-Marie Lehn\u2019 is a tremendous honor. Science thrives on cross-cultural exchange, and I\u2019m grateful that we live in a Europe where this exchange is both encouraged and easily possible. Our teams complement each other perfectly, and we share the goal of discovering innovative compounds to treat common cancers.\u201d<\/p>\n\n\n\n<p>Prof. Stefanie Kaiser added: \u201cEva and I met in 2022 at the fringes of an RNA research conference in Bonn. That\u2019s where we began developing ideas to collaborate on the enzyme METTL6, which is often overexpressed in liver and breast cancer cells and contributes to uncontrolled tumor growth. We now publish regularly together \u2013 with Eva\u2019s team in Grenoble contributing expertise in structural analysis, while my team in Frankfurt investigates the cellular effects of METTL6 modifications.\u201d<\/p>\n\n\n\n<p>Stefanie Kaiser studied pharmacy and holds extensive expertise in biomedicine and chemistry. Since 2020, she has served as Professor of Pharmaceutical Chemistry at Goethe University Frankfurt. Her academic career included earlier stays at Ludwig-Maximilians-Universit\u00e4t Munich and the Massachusetts Institute of Technology (MIT) in Cambridge, USA.<\/p>\n\n\n\n<p>Biologist Eva Kowalinski currently leads a research group at the European Molecular Biology Laboratory (EMBL) in Grenoble, focusing on the structural biology of macromolecular protein-RNA complexes involved in RNA modification. She also serves as Co-Chair of EMBL\u2019s infection biology program. Her academic background includes positions at Heidelberg University, Uppsala University (Sweden), and the Max Planck Institute of Biochemistry in Munich.<\/p>\n\n\n\n<p class=\"has-background\" style=\"background-color:#eeeeee\"><strong>Further information:<\/strong> <a href=\"https:\/\/www.dfh-ufa.org\/fr\/communiquesdepresse\/deutsch-franzoesischer-forcheurs-preis-zeichnet-projekt-im-bereich-krebsforschung-aus\" target=\"_blank\" rel=\"noreferrer noopener\">Press release of the Franco-German University (in French)<\/a><\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>RNA researchers Prof. Stefanie Kaiser from Goethe University Frankfurt and Dr. Eva Kowalinski from EMBL in Grenoble, France, have been awarded the Franco-German science prize \u201cPrix Forcheurs Jean-Marie Lehn\u201d. The [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":84585,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":"","_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"footnotes":""},"categories":[126,254],"tags":[243,244,245],"post_folder":[],"class_list":["post-84586","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-english","category-research","tag-biochemistry","tag-chemistry","tag-pharmacy"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>RNA Researchers from Frankfurt and Grenoble Receive Franco-German Science Award | Aktuelles aus der Goethe-Universit\u00e4t Frankfurt<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/aktuelles.uni-frankfurt.de\/en\/english\/rna-researchers-from-frankfurt-and-grenoble-receive-franco-german-science-award\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"RNA Researchers from Frankfurt and Grenoble Receive Franco-German Science Award | Aktuelles aus der Goethe-Universit\u00e4t Frankfurt\" \/>\n<meta property=\"og:description\" content=\"RNA researchers Prof. Stefanie Kaiser from Goethe University Frankfurt and Dr. Eva Kowalinski from EMBL in Grenoble, France, have been awarded the Franco-German science prize \u201cPrix Forcheurs Jean-Marie Lehn\u201d. 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