A New Biosynthesis Method Has Been Developed to Produce Antibiotics from Natural Substances
The use of the element fluorine to modify active substances is an important tool in modern drug development. A team
The use of the element fluorine to modify active substances is an important tool in modern drug development. A team
The respiratory chain plays a central role in energy metabolism of the cell. It is localized in mitochondria, the cell´s
Certain regions of the SARS-CoV-2 genome might be a suitable target for future drugs. This is what researchers at Goethe
An extended application of the CRISPR-Cas technology has been made possible by Dr Manual Kaulich’s team at Goethe University: the
Whether bacteria are resistant to antibiotics is often decided at the cell membrane. This is where antibiotics can be blocked
For the development of drugs or vaccines against COVID-19, research needs virus proteins of high purity. For most of the
When a cell is infected, SARS-CoV-2 not only causes the host cell to produce new virus particles. The virus also
Whether we smell, taste or see, or when adrenaline rushes through our veins, all of these signals are received by
What opportunities to create trust do social conflicts offer? What happens when neutron stars merge and produce gravitational waves and
At the heart of the PROXIDRUGS cluster lies the development of novel drugs that systematically degrade disease-relevant proteins in the
An ischemic stroke is an extreme disturbance of the homeostasis of brain and body. Among other things, the immune system
Researchers at Goethe University Frankfurt and the university of Würzburg have developed a new compound for treating cancer. It destroys
An interdisciplinary team from Frankfurt and Jena has developed a kind of bait with which to fish protein complexes out
A team of biochemists and virologists at Goethe University and the Frankfurt University Hospital were able to observe how human
Global health concerns us all. So does scientific progress, yet less immediate. The current worldwide corona pandemic has a tremendous
PROXIDRUGS, the regional network led by Goethe University, aims at developing active molecules for selective intervention, opening new therapeutic avenues.
FRANKFURT. Even more detailed insights into the cell will be possible in future with the help of a new development
When cells are stressed, they initiate a complex and precisely regulated response to prevent permanent damage. One of the immediate
Prolongation of Collaborative Research Centre on selective autophagy led by Goethe University. Four years ago, Collaborative Research Centre (CRC) 1177
The nervous system of the threadworm C. elegans is simple at first sight: it consists of 302 neurons, some of
Frankfurt researchers have explained the mechanism of regulator SidJ in detail / Accelerated publication in Nature In order to control
Microorganisms often assemble natural products similar to product assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS), play a key role
Professor Robert Tampé, Director of the Institute of Biochemistry at Goethe University, has been elected to the European Organization for
Professor Ivan Dikic, Director of the Institute of Biochemistry II, has been elected to the venerable American Academy of Arts
Bacteria can protect themselves from the attack of free radicals using specific natural products in their membranes. The biosynthesis of
Direct coupling of two molecules of nitrogen: chemists from Würzburg and Frankfurt have achieved what was thought to be impossible.
CRISPR/Cas enables the targeted deactivation of genes by cutting DNA at pre-determined sites. This is accomplished by providing the Cas
For decades it was assumed that protein channels and protein pumps fulfilled completely different functions and worked independently of each
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